SPINA - Structure Parameter Inference Approach
SPINA (Structure Parameter Inference Approach) is a
methodology to calculate constant structure parameters of
endocrine homeostatic systems from steady-state hormone and
metabolite concentrations. Methods and equations for thyroid
homeostasis (SPINA Thyr) have been described in Dietrich et al.
(2012) <doi:10.1155/2012/351864> and Dietrich et al. (2016)
<doi:10.3389/fendo.2016.00057>, and for glucose homeostasis
(SPINA Carb) in Dietrich et al. (2022)
<doi:10.1038/s41598-022-22531-3> and Dietrich et al. (2024)
<doi:10.1111/1753-0407.13525>.